Melatonin supplementation for sleep improvement has increased 425 per cent over the last two decades, with the number of persons taking big doses (more than 5 milligrams per day) reaching an all-time high, according to a study published in the journal JAMA on Feb. 1, 2022.
These findings raise concerns about potential safety hazards. As with other supplements, melatonin products are not regulated or held to the same quality standards as prescription medications. The authors noted that the real amount of melatonin contained in a pill may be much larger than the amount indicated on the label. This can result in people taking too much, especially because many people use melatonin on a regular basis.
While moderate dosages of melatonin used in the short term are generally regarded safe, excessive levels given over an extended period of time might bring side effects such as nausea, dizziness, headaches, and anxiety.
Melatonin dubbed the "sleep hormone," regulates your circadian rhythm (24-hour internal clock). Melatonin tablets may help some people fall asleep more quickly, but they have a little influence on sleeping through the night.
