The new drug, called zuranolone (Zurzuvae), works quickly and was officially approved on August 4, 2023. What's even better? It's a short two-week course. Until now, the only other approved medication for postpartum depression was brexanolone (Zulresso), but it needed to be given through a hospital-based IV.
Postpartum depression shares symptoms with other types of depression, such as deep sadness, feeling tired all the time, losing interest in regular activities, and struggling with thinking and memory. In severe cases, women might even have thoughts of hurting themselves or their baby.
The introduction of this pill is not just a medical breakthrough; it's also expected to lessen the stigma around postpartum depression. By offering a more accessible treatment option, it aims to encourage more women to seek the help they need. This is a positive step forward for the well-being of new moms everywhere!
Getting a breast cancer diagnosis can be scary, but things have changed a lot in how we treat it. Unlike the old days when everyone got the same treatment, now it's like having a personalized toolkit to fight the disease.
Survival rates have gone up, with only 5% of women at an average risk of dying within five years after a breast cancer diagnosis, down from 14% in the 1990s. Dr. Harold Burstein from the Dana-Farber Cancer Institute explains, We may not always know why someone gets breast cancer, but the good news is that outcomes are improving.
Instead of using a one-size-fits-all approach, scientists can now categorize breast tumors based on cell type. This allows for tailor-made combinations of treatments. Surgery is still common, but chemotherapy might be smaller or skipped. New drugs like immunotherapy and targeted therapies are giving doctors more options.
Breast cancer comes in different types, like ER-positive or HER2-positive. Knowing this helps doctors choose the best treatments. Thanks to research in the last decade, tests can now identify gene mutations, predict tumor growth, and help customize treatments.
For ER-positive, HER2-negative breast cancer, the use of chemotherapy has become more selective. Powerful tools allow doctors to decide if a patient really needs it. Medications like CDK4/6 inhibitors are also used for high-risk cases.
HER2-positive breast cancer, a more aggressive type, has seen progress with targeted therapies like Herceptin. A new approach pairs chemotherapy with proteins for better results with fewer side effects.
Triple-negative breast cancer, a fast-growing type, is challenging, but new drugs and immunotherapy are showing promise. Even more promising is the future use of liquid biopsies, blood tests that can guide treatment based on circulating tumor DNA.
Dr. Burstein is optimistic about the coming years, mentioning new technologies like liquid biopsies. For metastatic breast cancer, which isn't curable yet, patients are living longer with new treatments improving their lives.
Inflammatory breast cancer (IBC) is rare but dangerous. Unlike other types, it doesn't always show a lump. Symptoms develop rapidly, and early signs are often mistaken for less serious issues. Dr. Filipa Lynce advises not to ignore changes in the breast, even without a lump. If symptoms persist, seeking medical attention is crucial.
Finally, for women diagnosed with breast cancer, a multidisciplinary care team is essential. Collaboration among specialists and communication with your healthcare team are key to better outcomes. Don't hesitate to ask questions and be an active part of your treatment plan.
Seasonal affective disorder can be treated and managed with the use of light therapy and medicines.
The winter season brings chilly days and cozy vibes, but for some, it also ushers in a condition known as Seasonal Affective Disorder (SAD). SAD is a form of depression that kicks in during late fall and winter, easing off with the arrival of spring. While the exact cause remains a mystery, researchers believe a lack of sunlight plays a pivotal role.
Dr. Richard Schwartz, an associate professor of psychiatry at Harvard-affiliated McLean Hospital, emphasizes the significance of recognizing SAD as a serious condition. He notes, "People should not ignore the signs of SAD and should seek treatment if they appear, as left alone, SAD can escalate to serious health issues."
Sunlight and Your Mood
Sunlight exposure has a profound impact on our brains. It stimulates the hypothalamus, a brain region housing our internal sleep-wake clock. Insufficient light disrupts this clock, leading to an overproduction of the sleep hormone melatonin and a decrease in serotonin, the feel-good brain chemical. This chemical imbalance can result in feelings of low energy, lethargy, and depression.
SAD comes with other telltale signs, including diminished sexual desire, an inclination to overeat (especially comfort foods), and sleep disturbances. It also correlates with cognitive challenges like difficulties in concentration and memory. Dr. Schwartz adds, "As you become more lethargic from SAD, you are also less likely to exercise or socialize."
Several factors heighten the risk of SAD, such as a family history of SAD or depression and geographic location. People residing in northern states, where daylight diminishes significantly in fall and winter, are more prone to SAD than those in the south.